Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

E-MTAB-6496

ABSTRACT: RNA-seq of primary murine (C57BL/6J) LSK cells overexpressing miR-10a or miR-335

PROVIDER: E-MTAB-6496 | ExpressionAtlas | 2018-09-17

REPOSITORIES: ExpressionAtlas

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	E-MTAB-6496-analysis-methods.tsv	Tabular
	E-MTAB-6496-analytics.tsv	Tabular
	E-MTAB-6496-atlasExperimentSummary.Rdata	Rdata
	E-MTAB-6496-configuration.xml	Xml
	E-MTAB-6496-g1_g2-mvaPlot.png	Other

Items per page:

1 - 5 of 32

Similar Datasets

RNA-seq of primary murine (C57BL/6J) LSK cells overexpressing miR-10a miR-335.

Project description:RNA-seq of primary murine (C57BL/6J) LSK cells overexpressing miR-10a miR-335.

| PRJEB24979 | ENA

Niche Derived Netrin-1 Regulates Hematopoietic Stem Cell Dormancy via its Receptor Neogenin-1

Project description:We have performed RNA-seq in highly purified Hematopoeitic Stem cells (HSC, LSK/SLAM) from young (4-5mo) and old (20-24mo) C57BL/6J in order to investigate differences in gene expression between these groups.

2020-10-20 | GSE128050 | GEO

HDAC6 deacetylates IDH1 to regulate the homeostasis of hematopoietic stem/progenitor cells

Project description:In order to further explore the mechanism by which increased 5hmC inhibits expansion of LSK cells from Hdac6-/- murine primary BM cells, we performed RNA sequencing (RNA-seq) analysis using LSK cells isolated from Hdac6-/- and WT mice.

2022-05-21 | GSE203239 | GEO

A comprehensive transcriptome signature of murine hematopoietic stem cell aging

Project description:We have performed ATAC-seq in highly purified Hematopoeitic Stem cells (HSC, LSK/SLAM) from young (4-5mo) and old (20-24mo) C57BL/6J in order to investigate differences in chromatin accessible sites between these 2 groups.

2021-04-02 | GSE166674 | GEO

RNA-seq of primary murine (C57BL/6J) LSK cells overexpressing miR-10a or miR-335

Project description:In this experiment, we want to assess the effect of a lentiviral miR-10a and miR-335 overexpression on the transcriptome of murine LSK (Lin-,Sca-1+,c-Kit+) cells. Primary LSK cells were transduced with lentiviral miRNA overexpression constructs (control: GFP overexpression) and sorted for transduced cells (GFP+) after five days of in vitro culture (Flt-3, TPO, IL-3, SCF containing media).

2018-06-01 | E-MTAB-6496 | biostudies-arrayexpress

Single-cell RNA sequencing of bone marrow cells and spleen isolated from mice after sham surgery or myocardial infarction, followed by treatments (vehicle/4-oxo-RA)

Project description:Study of the impact of 4-oxo-RA on LSK (bone marrow and spleen) cell characteristics post-myocardial infarction in C57BL/6J mice. Myocardial infarction was induced in female C57BL/6J mice (aged 6 to approximately 12 weeks) through LAD occlusion. Post-surgery, mice were intraperitoneally injected with 30 mg/kg 4-oxo-RA (MI+4-oxo-RA) or the equivalent DMSO in PBS (MI+vehicle) on the 1st and 2nd days after MI. Three days post-MI, mice were euthanized. ScRNA-seq was performed on 25k LSK cells (Lin-, Sca1+, c-Kit+) that were facs sorted.

2025-02-06 | E-MTAB-13510 | biostudies-arrayexpress

HDAC6 deacetylates IDH1 to regulate the homeostasis of hematopoietic stem/progenitor cells [WGBS-seq]

Project description:In order to further explore the mechanism by which increased 5hmC inhibits expansion of LSK cells from Hdac6-/- murine primary BM cells, we performed WGBS-seq and oxWGBS-seq analysis using LSK cells isolated from Hdac6-/- and WT mice.

2023-06-06 | GSE234147 | GEO

RNA-seq of mouse cultured retinal pigment epithelium (RPE) challenged with photoreceptor outer segments (POS).

Project description:Primary culture of mouse RPE cells (C57BL/6J background) was challenged with POS for 90 min and subjected for RNA-seq.

2017-04-03 | GSE96626 | GEO

RNA-seq of miR-204-5p overexpressing 4T1 murine breast cancer cells

Project description:RNA-seq of miR-204-5p overexpressing 4T1 murine breast cancer cells

| PRJNA431801 | ENA

Dynamic DNA methylation reveals novel cis-regulatory elements in murine hematopoiesis

Project description:Genome wide DNA methylation profiling of 9 different cell types of the murine hematopoietic system. The samples comprise FACS-sorted biological triplicates of hematopoietic stem and progenitor cells (LSK, CMP, GMP, MEP) and terminally differentiated immune cells (monocytes, neutrophils, CD4+ T-cells, CD8+ T-cells, B-cells). Additionally, bone marrow of CD45.1 (B6.SJL-Ptprca Pepcb/BoyCrl) and CD45.2 (C57BL/6J) mice as well as JAK2-V617F mutant mice was analyzed. The Illumina Infinium Mouse Methylation BeadChip was used to generate DNA methylation profiles across approximately 285,000 CpGs in these samples.

2022-11-08 | GSE201923 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data