Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: 196
SUBMITTER: Nicolas Le Novère
PROVIDER: BIOMD0000000005 | BioModels | 2024-09-02
REPOSITORIES: BioModels
Items per page: 5 1 - 5 of 17 |
Proceedings of the National Academy of Sciences of the United States of America 19910801 16
The proteins cdc2 and cyclin form a heterodimer (maturation promoting factor) that controls the major events of the cell cycle. A mathematical model for the interactions of cdc2 and cyclin is constructed. Simulation and analysis of the model show that the control system can operate in three modes: as a steady state with high maturation promoting factor activity, as a spontaneous oscillator, or as an excitable switch. We associate the steady state with metaphase arrest in unfertilized eggs, the s ...[more]