Ontology highlight
ABSTRACT:
SUBMITTER: Johannes Meyer
PROVIDER: BIOMD0000000838 | BioModels | 2024-09-02
REPOSITORIES: BioModels
Items per page: 1 - 5 of 12 |
Journal of theoretical biology 20190930
Immune checkpoint inhibitors (ICI) are becoming widely used in the treatment of metastatic melanoma. However, the ability to predict the patient's benefit from these therapeutics remains an unmet clinical need. Mathematical models that predict melanoma patients' response to ICI can contribute to better informed clinical decisions. Here, we developed a simple mathematical population model for pembrolizumab-treated advanced melanoma patients, and analyzed the local and global dynamics of the syste ...[more]