Dataset Information

Pawelek2016 - Within-Host Models of High and Low Pathogenic Influenza Virus Infections

ABSTRACT: a possible mechanism of MP in determining HP versus LP outcomes, and how different interventions might affect infection dynamics

SUBMITTER: Sarubini Kananathan

PROVIDER: MODEL1812040006 | BioModels | 2020-07-09

REPOSITORIES: BioModels

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Publications

Within-Host Models of High and Low Pathogenic Influenza Virus Infections: The Role of Macrophages.

Pawelek Kasia A KA Dor Daniel D Salmeron Cristian C Handel Andreas A

PloS one 20160226 2

The World Health Organization identifies influenza as a major public health problem. While the strains commonly circulating in humans usually do not cause severe pathogenicity in healthy adults, some strains that have infected humans, such as H5N1, can cause high morbidity and mortality. Based on the severity of the disease, influenza viruses are sometimes categorized as either being highly pathogenic (HP) or having low pathogenicity (LP). The reasons why some strains are LP and others HP are no ...[more]

PMID: 26918620

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