Hutchinson2016 - Vascular phenotype identification and anti-angiogenic treatment recommendation
Ontology highlight
ABSTRACT:
SUBMITTER: 
Johannes Meyer
PROVIDER: MODEL1911130007 | BioModels | 2019-11-13
REPOSITORIES: BioModels
Dataset's files
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Publications
Vascular phenotype identification and anti-angiogenic treatment recommendation: A pseudo-multiscale mathematical model of angiogenesis.
Hutchinson L G LG Gaffney E A EA Maini P K PK Wagg J J Phipps A A Byrne H M HM
Journal of theoretical biology 20160314
The development of anti-angiogenic drugs for cancer therapy has yielded some promising candidates, but novel approaches for interventions to angiogenesis have led to disappointing results. In addition, there is a shortage of biomarkers that are predictive of response to anti-angiogenic treatments. Consequently, the complex biochemical and physiological basis for tumour angiogenesis remains incompletely understood. We have adopted a mathematical approach to address these issues, formulating a spa ...[more]
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