Ontology highlight
ABSTRACT:
SUBMITTER: Mohammad Umer Sharif Shohan
PROVIDER: MODEL1912170005 | BioModels | 2020-01-06
REPOSITORIES: BioModels
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MODEL1912170005?filename=Yakimchuk2019.cps | Other | |||
MODEL1912170005?filename=Yakimchuk2019.xml | Xml |
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Bio Systems 20191114
The cellular and molecular mechanisms of immunomodulatory actions of glucocorticoids (GC) remain to be identified. Using our experimental findings, a mathematical model based on a system of ordinary differential equations for characterization of the regulation of anti-tumor immune activity by the both direct and indirect GC effects was generated to study the effects of GC treatment on effector CD8<sup>+</sup> T cells, GC-generated tolerogenic dendritic cells (DC), regulatory T cells and the grow ...[more]