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Erythrocyte model of the hemoglobin oxygen dissociation curve.

ABSTRACT: This file contains the models, simulation, and generated data that were used in the manuscript "Erythrocyte Metabolism". The equations used to create the models were derived from the paper by Dash et al. 2016 (doi: 10.1007/s00421-015-3228-3). The equations used to calculate the capillary erythrocyte transit time were derived from Richardson et al. 1994 (doi 10.1007/978-1-4615-1875-4_91). The code for the models and computations was created using the R language. Finally, the file was downloaded from the GitHub repository that is associated with the manuscript: https://github.com/PanosChatzi/Erythrocyte-Metabolism

SUBMITTER: Panagiotis N Chatzinikolaou  

PROVIDER: MODEL2305140001 | BioModels | 2024-04-29

REPOSITORIES: BioModels

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Publications

Our aim is to present an updated overview of the erythrocyte metabolism highlighting its richness and complexity. We have manually collected and connected the available biochemical pathways and integrated them into a functional metabolic map. The focus of this map is on the main biochemical pathways consisting of glycolysis, the pentose phosphate pathway, redox metabolism, oxygen metabolism, purine/nucleoside metabolism, and membrane transport. Other recently emerging pathways are also curated,  ...[more]