Dataset Information

Feist2007_EcMetabol_flux1

ABSTRACT: organism E. coli K-12 MG1655 model iAF1260 Biomass Objective Function (BOF) Ec_biomass_iAF1260_core_59p81M (E. coli biomass objective function (iAF1260) - core - with 59.81 GAM estimate) flux balance analysis objective maximize BOF Growth Associated Maintenance (GAM) 59.81 mmol ATP gDW-1 Non-Growth Associated Maintenance (NGAM) 8.39 mmol ATP gDW-1 hr-1 media conditions computational minimal media carbon source 8 mmol glucose gDw-1 hr-1 aerobic or anaerobic 18.5 mmol O2 gDw-1 hr-1 additional constraints reactions constrained to zero CAT, SPODM, SPODMpp, FHL flux split between reaction pairs none This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not.. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.

SUBMITTER: Molecular Systems Biology

PROVIDER: MODEL3023609334 | BioModels | 2005-01-01

REPOSITORIES: BioModels

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Publications

A genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic information.

Feist Adam M AM Henry Christopher S CS Reed Jennifer L JL Krummenacker Markus M Joyce Andrew R AR Karp Peter D PD Broadbelt Linda J LJ Hatzimanikatis Vassily V Palsson Bernhard Ø BØ

Molecular systems biology 20070626

An updated genome-scale reconstruction of the metabolic network in Escherichia coli K-12 MG1655 is presented. This updated metabolic reconstruction includes: (1) an alignment with the latest genome annotation and the metabolic content of EcoCyc leading to the inclusion of the activities of 1260 ORFs, (2) characterization and quantification of the biomass components and maintenance requirements associated with growth of E. coli and (3) thermodynamic information for the included chemical reactions ...[more]

PMID: 17593909

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