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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of Arabidopsis plants after heat shock or treatment with HSP90 inhibitors (geldanamycin and radicicol)

ABSTRACT: Effect of heat shock or HSP90 inhibitors (geldanamycin and radicicol) on wild type Arabidopsis thaliana.

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Kenji Yamada

PROVIDER: E-ATMX-12 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Cytosolic HSP90 regulates the heat shock response that is responsible for heat acclimation in Arabidopsis thaliana.

Yamada Kenji K Fukao Yoichiro Y Hayashi Makoto M Fukazawa Mitsue M Suzuki Iku I Nishimura Mikio M

The Journal of biological chemistry 20071027 52

Plant survival requires the ability to acclimate to heat. When plants are subjected to heat shock, the expression of various genes is induced, and the plants become tolerant of higher temperatures. We found that transient treatment with geldanamycin and radicicol, two heat shock protein 90 (HSP90) inhibitors, induced heat-inducible genes and heat acclimation in Arabidopsis thaliana seedlings. Heat shock reduced the activity of exogenously expressed glucocorticoid receptor (GR). Since GR activity ...[more]

PMID: 17965410

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