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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Comparative genomic hybridization of disease causing strains of Campylobacter jejuni

ABSTRACT: Data is also available from http://bugs.sgul.ac.uk/E-BUGS-22

INSTRUMENT(S): Variable Atmosphere Incubator, GeneQuant DNA/RNA caluculator

ORGANISM(S): Campylobacter jejuni

SUBMITTER:

PROVIDER: E-BUGS-22 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Comparative phylogenomics of the food-borne pathogen Campylobacter jejuni reveals genetic markers predictive of infection source.

Champion Olivia L OL Gaunt Michael W MW Gundogdu Ozan O Elmi Abdi A Witney Adam A AA Hinds Jason J Dorrell Nick N Wren Brendan W BW

Proceedings of the National Academy of Sciences of the United States of America 20051017 44

Campylobacter jejuni is the predominant cause of bacterial gastroenteritis worldwide, but traditional typing methods are unable to discriminate strains from different sources that cause disease in humans. We report the use of genomotyping (whole-genome comparisons of microbes using DNA microarrays) combined with Bayesian-based algorithms to model the phylogeny of this major food-borne pathogen. In this study 111 C. jejuni strains were examined by genomotyping isolates from humans with a spectrum ...[more]

PMID: 16230626

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