Porphyromonas gingivalis: Control (Wild-type W83) vs. its htrA mutant
Ontology highlight
ABSTRACT:
ORGANISM(S): Porphyromonas gingivalis
SUBMITTER: Paulo Rodrigues
PROVIDER: E-GEOD-10027 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Porphyromonas gingivalis htrA is involved in cellular invasion and in vivo survival.
Yuan Lihui L Rodrigues Paulo H PH Bélanger Myriam M Dunn William A WA Progulske-Fox Ann A
Microbiology (Reading, England) 20080401 Pt 4
HtrA is a heat-stress protein that functions both as a chaperone and as a serine protease. HtrA has been shown in several organisms to be involved in responses to stressful environmental conditions and involvement of HtrA in virulence has been reported in pathogenic species. A Porphyromonas gingivalis htrA mutant demonstrated no significant difference to the W83 parent strain when subjected to high temperature and pH values from 3 to 11. However, the htrA mutant showed increased sensitivity to H ...[more]
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