Unknown,Transcriptomics,Genomics,Proteomics

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Transcriptome analysis of Streptococcus mutans biofilms in response to cranberry proanthocyanidins


ABSTRACT: The influence of cranberry proanthocyanidins on the transcriptomic responses of Streptococcus mutans during biofilm formation was investigated. Treatment regimens simulating topical exposures experienced clinically (twice-daily, 60 s each) were used over saliva-coated hydroxyapatite biofilm model. Cranberry proanthocyanidins (1.5 mg/ml) in 15% ethanol was used to treat the biofilms. Four biological replicates each for the treatment and vehicle control were used for RNA extraction and microarray.

ORGANISM(S): Streptococcus mutans UA159

SUBMITTER: Guoping Feng 

PROVIDER: E-GEOD-40172 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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