Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Jean-Luc Mougeot
PROVIDER: E-GEOD-10746 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20110908 4
<h4>Objective</h4>Understanding the pathogenesis of chemotherapy-induced oral mucositis (CIOM) is vital to develop therapies for this common, dose-limiting side effect of cancer treatment. We investigated molecular events in CIOM from buccal mucosa tissue collected before and 2 days after chemotherapy from patients with acute myeloid leukemia (AML) and healthy controls by microarray analysis.<h4>Methods</h4>Microarray analysis was performed using Human Genome U133 Plus 2.0 Array on buccal mucosa ...[more]