Unknown,Transcriptomics,Genomics,Proteomics

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TEV-Arabidopsis pathosystem


ABSTRACT: Transcription profiling of Arabidopsis plants infected with the Tobacco etch potyvirus TEV and the evolved TEV-At17, which was generated by serial passes of ancestral TEV in Arabidopsis. Infection with TEV-At17 cause severe symptoms in the plant, compared with the asymptomatic TEV-infection. Keywords: Virus infection Five replicates for each sample category (Arabidopsis Ler infected with mock, or with TEV and TEV-At17 viruses) were generated, and compared with a global reference, generated from an equimolar mix of amplified RNAs from each of the 15 plants. Three replicas (#1,2, and 3) in each group were labeled with Cy5 and compared with Cy3-labeled reference mix, while the other two replicas (#4 and 5) were reversed-labeled.

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Miguel Perez-Amador 

PROVIDER: E-GEOD-11088 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Virus adaptation by manipulation of host's gene expression.

Agudelo-Romero Patricia P   Carbonell Pablo P   Perez-Amador Miguel A MA   Elena Santiago F SF  

PloS one 20080611 6


Viruses adapt to their hosts by evading defense mechanisms and taking over cellular metabolism for their own benefit. Alterations in cell metabolism as well as side-effects of antiviral responses contribute to symptoms development and virulence. Sometimes, a virus may spill over from its usual host species into a novel one, where usually will fail to successfully infect and further transmit to new host. However, in some cases, the virus transmits and persists after fixing beneficial mutations th  ...[more]

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