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GNF mouse atlas_macrophages

ABSTRACT: Monocytes and macrophages express an extensive repertoire of G Protein-Coupled Receptors (GPCRs) that regulate inflammation and immunity. In this study we performed a systematic microarray analysis of GPCR expression in primary mouse tissues to identify family members that are either enriched in macrophages compared to a panel of other cell types, or are regulated by an inflammatory stimulus, the bacterial product lipopolysaccharide (LPS). Keywords: macrophage Macrophage, osteoblast, osteoclast, and mast cell samples were profiled on our GNF1M array.

ORGANISM(S): Mus musculus

SUBMITTER: John Walker

PROVIDER: E-GEOD-11339 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Expression analysis of G Protein-Coupled Receptors in mouse macrophages.

Lattin Jane E JE Schroder Kate K Su Andrew I AI Walker John R JR Zhang Jie J Wiltshire Tim T Saijo Kaoru K Glass Christopher K CK Hume David A DA Kellie Stuart S Sweet Matthew J MJ

Immunome research 20080429

<h4>Background</h4>Monocytes and macrophages express an extensive repertoire of G Protein-Coupled Receptors (GPCRs) that regulate inflammation and immunity. In this study we performed a systematic micro-array analysis of GPCR expression in primary mouse macrophages to identify family members that are either enriched in macrophages compared to a panel of other cell types, or are regulated by an inflammatory stimulus, the bacterial product lipopolysaccharide (LPS).<h4>Results</h4>Several members o ...[more]

PMID: 18442421

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