Transcription profiling of human peripheral blood mononuclear cells before and after exercise
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Peter Connolly
PROVIDER: E-GEOD-1140 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Effects of exercise on gene expression in human peripheral blood mononuclear cells.
Connolly Peter H PH Caiozzo Vincent J VJ Zaldivar Frank F Nemet Dan D Larson Jennifer J Hung She-Pin SP Heck J Denis JD Hatfield G Wesley GW Cooper Dan M DM
Journal of applied physiology (Bethesda, Md. : 1985) 20040611 4
Exercise leads to increases in circulating levels of peripheral blood mononuclear cells (PBMCs) and to a simultaneous, seemingly paradoxical increase in both pro- and anti-inflammatory mediators. Whether this is paralleled by changes in gene expression within the circulating population of PBMCs is not fully understood. Fifteen healthy men (18-30 yr old) performed 30 min of constant work rate cycle ergometry (approximately 80% peak O2 uptake). Blood samples were obtained preexercise (Pre), end-ex ...[more]
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