Transcriptional responses of Saccharomyces cerevisiae to carbon and nitrogen deprivation
Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Patrick Bradley
PROVIDER: E-GEOD-11754 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Coordinated concentration changes of transcripts and metabolites in Saccharomyces cerevisiae.
Bradley Patrick H PH Brauer Matthew J MJ Rabinowitz Joshua D JD Troyanskaya Olga G OG
PLoS computational biology 20090130 1
Metabolite concentrations can regulate gene expression, which can in turn regulate metabolic activity. The extent to which functionally related transcripts and metabolites show similar patterns of concentration changes, however, remains unestablished. We measure and analyze the metabolomic and transcriptional responses of Saccharomyces cerevisiae to carbon and nitrogen starvation. Our analysis demonstrates that transcripts and metabolites show coordinated response dynamics. Furthermore, metaboli ...[more]
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