Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcription profiling of human breast cancers (30)

ABSTRACT: We used microarrays to profile 30 human primary breast tumors and determine global gene expression patterns and molecular subtypes Experiment Overall Design: RNA from SNAP frozen human tumor biopsies was analyzed on Affymetrix mircroarrays

ORGANISM(S): Homo sapiens

SUBMITTER: Tom Januario

PROVIDER: E-GEOD-12763 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Gene expression profiling of 30 human breast cancers

Project description:We used microarrays to profile 30 human primary breast tumors and determine global gene expression patterns and molecular subtypes Keywords: Basal gene expression in human tumor samples

2009-01-12 | GSE12763 | GEO

RNAseq analysis of ruxolitinib treated breast cancers

Project description:We performed RNA sequencing analysis on fresh-frozen biopsies of metastatic triple-negative breast cancer prior to undergoing therapy with ruxolitinib, or after 2 cycles of therapy in a subset of patients.

2018-11-05 | GSE107000 | GEO

Breast Cancer Gene Expression Data from Hamburg Series

Project description:Gene expression profiling of surgical biopsies from 74 breast cancer patients of different subtypes from Hamburg dataset. Fresh frozen pre-treatment surgical biopsy samples from breast cancer patients were analyzed on Affymetrix HGU133A.

2014-04-17 | E-GEOD-46184 | biostudies-arrayexpress

Micro-RNA expression signatures in breast cancer progression

Project description:miRNA expression in breast cancer progression, from normal breast tissue to DCIS to subtype-specific invasive breast carcinomas. Two separate datasets are used, of which this is one. The other is also publicly available. These samples are collected at Akershus Univeristy Hospital, Norway, as part of a consecutive series and total RNA is extracted from snap-frozen biopsies.

2016-04-30 | E-MTAB-3759 | biostudies-arrayexpress

Epigenome analysis of tumor adjacent normal tissue from breast cancer patients

Project description:Genome wide DNA methylation profiling of tumor adjacent normal tissue from patients with invasive breast cancer, as well as tissue from women undergoing reduction mammoplasty or prophylactic surgery. The Illumina Infinium 450k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 485,577 CpGs in snap frozen breast tissue. Samples included 70 tumor-adjacent normal breast tissue with invasive disease, 8 tissues from breast prophylactic patients, and 18 tissues from breast reduction patients.

2015-04-15 | GSE67919 | GEO

Microdissected tumor epithelium and tumor stroma from patients with breast cancer

Project description:Stratification of breast cancers into subtypes are generally based on immune assays on tumor cells and/or mRNA expression of tumor cell enriched tissues. Here, we have laser microdissected tumor epithelium and tumor stroma from 24 breast cancer biopsies (12 luminal-like and 12 basal-like). We hypothesized that the stromal proteome would separate patients with breast into groups independently of the traditional epithelial based subtypes.

2023-06-23 | PXD027012 | Pride

Gene expression profiling of primary HER2-positive breast cancers treated with neoadjuvant trastuzumab

Project description:Trastuzumab, a humanized monoclonal antibody directed to the HER2 protein, is the standard-of-care treatment for patients with HER2 positive breast cancer, reducing the risk of relapse and death in patients. Nonetheless, some patients do not benefit from this treatment, underscoring the need to identify patients for whom chemotherapy + trastuzumab is adequate versus patients requiring additional drugs. The series comprised 24 incisional biopsies of breast carcinomas derived from patients that received neoadjuvant trastuzumab based therapy. Gene expression profiling was performed using RNA from frozen core biopsies from 24 patients with primary HER2-positive (HER2+) tumors treated with neoadjuvant chemotherapy and trastuzumab.

2016-03-31 | E-GEOD-62327 | biostudies-arrayexpress

Breast Cancer. Ull-series. 167 samples

Project description:167 Ull-samples 244k array Tumor tissue from a series of 212 primary breast cancers were sequentially collected at Ullevål University Hospital, Oslo, Norway between 1990 and 1994. Tissues were collected at the time of primary surgery and snap frozen. We performed aCGH on 167 of these samples. DNA was isolated using chloroform/phenol extraction, followed by ethanol precipitation. The aCGH-platform was the Agilent Human genome CGH Microarray 244k. The aim of this study was to investigate the genome wide genomic copy number alterations in a cohort of primary breast cancer patients.

2010-07-06 | GSE20394 | GEO

different expression of RNAs between breast cancer and benign tissue

Project description:To find differentially expressed RNAs between breast cancer and benign tissue, we have conducted whole genome microarray expression profiling as a discovery platform to identify genes that play a key role in the breast cancer progression. Primary cancer tissues and paired adjacent noncancerous tissues were snap-frozen in liquid nitrogen immediately after resection and were used to perform genome expression analysis.

2018-04-10 | GSE112848 | GEO

Transcription profiling of human breast carcinomas negative for estrogen, progesterone and HER2/nue receptors

Project description:97 triple negative tumors were selected from the fresh-frozen tissue bank of the Netherlands Cancer Institute and gene expression profiles were generated using 35K oligonucleotide microarrays. Human breast carcinomas were snap frozen in liquid nitrogen within one hour after surgery and stored in the fresh-frozen tissue bank of the Netherlands Cancer Institute. RNA from a pool of more than 100 unselected fresh frozen breast carcinomas were isolated and pooled to form the reference to which each individual breast carcinoma is hybridized.

2007-10-09 | E-NCMF-2 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data