MiRNA expression data in idiopathic pulmonary fibrosis

ABSTRACT: Idiopathic pulmonary fibrosis (IPF) is an untreatable fibrotic lung disease characterized by fibroblast proliferation and epithelial mesenchymal transition. The expression and role of microRNAs (miRNA) has not been studied in IPF. Using miRNA expression microarrays we identified 46 differentially expressed miRNA in IPF lungs which included let-7d and the miR-30 family. Keywords: miRNA expression Lung tissue samples for microarray analysis were obtained through the University of Pittsburgh Health Sciences Tissue Bank. Ten samples were obtained from surgical remnants of biopsies or lungs explanted from patients with IPF who underwent pulmonary transplant, and ten control normal lung tissues obtained from the disease free margins with normal histology of lung cancer resection specimens. The

ORGANISM(S): Homo sapiens

SUBMITTER: Kusum Pandit 

PROVIDER: E-GEOD-13316 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress