Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Kusum Pandit
PROVIDER: E-GEOD-27430 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
American journal of respiratory cell and molecular biology 20121004 6
In this study, we explored the regulation and the role of up-regulated microRNAs in idiopathic pulmonary fibrosis (IPF), a progressive interstitial lung disease of unknown origin. We analyzed the expression of microRNAs in IPF lungs and identified 43 significantly up-regulated microRNAs. Twenty-four of the 43 increased microRNAs were localized to the chromosome 14q32 microRNA cluster. We validated the increased expression of miR-154, miR-134, miR-299-5p, miR-410, miR-382, miR-409-3p, miR-487b, m ...[more]