Ontology highlight
ABSTRACT:
ORGANISM(S): Arabidopsis thaliana
SUBMITTER: Alexis Sarazin
PROVIDER: E-GEOD-13419 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Teixeira Felipe Karam FK Heredia Fabiana F Sarazin Alexis A Roudier François F Boccara Martine M Ciaudo Constance C Cruaud Corinne C Poulain Julie J Berdasco Maria M Fraga Mario F MF Voinnet Olivier O Wincker Patrick P Esteller Manel M Colot Vincent V
Science (New York, N.Y.) 20090129 5921
DNA methylation is essential for silencing transposable elements and some genes in higher eukaryotes, which suggests that this modification must be tightly controlled. However, accidental changes in DNA methylation can be transmitted through mitosis (as in cancer) or meiosis, leading to epiallelic variation. We demonstrated the existence of an efficient mechanism that protects against transgenerational loss of DNA methylation in Arabidopsis. Remethylation is specific to the subset of heavily met ...[more]