Unknown,Transcriptomics,Genomics,Proteomics

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RNAi profiling of human MCF-7 cells depleted for NAMPT knockdown


ABSTRACT: NAMPT is an enzyme in the mammalian NAD+ salvage pathway. Expression microarray analysis was used to study the effect of NAMPT knockdown on gene expression in MCF-7 breast cancer cells. Experiment Overall Design: Stable knockdown of NAMPT was achieved using a retroviral shRNA construct. An shRNA directed against Luciferase was used to generate the Luc control cells. Three independent biological replicates with matching Luc controls were analyzed using Affymetrix U133 A2.0 microarrays.

ORGANISM(S): Homo sapiens

SUBMITTER: Lee Kraus 

PROVIDER: E-GEOD-13449 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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