Ontology highlight
ABSTRACT:
ORGANISM(S): Streptomyces griseus subsp. griseus NBRC 13350
SUBMITTER: Sueharu Horinouchi
PROVIDER: E-GEOD-13804 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Microbiology (Reading, England) 20090423 Pt 7
A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) is a microbial hormone that triggers morphological differentiation and secondary metabolism in Streptomyces griseus. The effects of A-factor on global gene expression were determined by DNA microarray analysis of transcriptomes obtained with the A-factor-deficient mutant DeltaafsA. A-factor was added at a concentration of 25 ng ml(-1) to mutant DeltaafsA at the middle of the exponential growth phase, and RNA samples were prepared fro ...[more]