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Ethanol treated vs paired control

ABSTRACT: 6 ethanol treated animals with their paired controls Keywords: repeat sample Reference Design with 6 biological repeats (6 treated, 6 control, 12 reference)

ORGANISM(S): Rattus norvegicus

SUBMITTER: Rishi Khan

PROVIDER: E-GEOD-2718 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Chronic alcohol exposure alters transcription broadly in a key integrative brain nucleus for homeostasis: the nucleus tractus solitarius.

Covarrubias Maria Yolanda MY Khan Rishi L RL Vadigepalli Rajanikanth R Hoek Jan B JB Schwaber James S JS

Physiological genomics 20050927 1

Chronic exposure to alcohol modifies physiological processes in the brain, and the severe symptoms resulting from sudden removal of alcohol from the diet indicate that these modifications are functionally important. We investigated the gene expression patterns in response to chronic alcohol exposure (21-28 wk) in the rat nucleus tractus solitarius (NTS), a brain nucleus with a key integrative role in homeostasis and cardiorespiratory function. Using methods and an experimental design optimized f ...[more]

PMID: 16189278

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