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Lymph nodes with follicular lymphoma or reactive hyperplasia


ABSTRACT: Comparison of gene expression profiles of follicular lymphoma vs. reactive lymph nodes. 8 cases of follicular lymphoma; 5 cases of reactive lymph nodes.

ORGANISM(S): Homo sapiens

SUBMITTER: Jack Zhu 

PROVIDER: E-GEOD-14214 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications


Emerging technologies allow broad profiling of the cancer genome for differential DNA methylation relative to benign cells. Herein, bisulfite-modified DNA from lymph nodes with either reactive hyperplasia or follicular lymphoma (FL) were analyzed using a commercial C/UpG genotyping assay. Two hundred fifty-nine differentially methylated targets (DMT) distributed among 183 unique genes were identified in FL. Comparison of matched formalin-fixed, paraffin-embedded and frozen surgical pathology rep  ...[more]

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