Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Raja Jothi
PROVIDER: E-GEOD-14344 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Ho Lena L Jothi Raja R Ronan Jehnna L JL Cui Kairong K Zhao Keji K Crabtree Gerald R GR
Proceedings of the National Academy of Sciences of the United States of America 20090311 13
Distinctive SWI/SNF-like ATP-dependent chromatin remodeling esBAF complexes are indispensable for the maintenance and pluripotency of mouse embryonic stem (ES) cells [Ho L, et al. (2009) Proc Natl Acad Sci USA 10.1073/pnas.0812889106]. To understand the mechanism underlying the roles of these complexes in ES cells, we performed high-resolution genome-wide mapping of the core ATPase subunit, Brg, using ChIP-Seq technology. We find that esBAF, as represented by Brg, binds to genes encoding compone ...[more]