Unknown,Transcriptomics,Genomics,Proteomics

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Sok2 vs wild type colonies


ABSTRACT: Time course analyses of gene expression in sok2 deleted vs wild type colonies during late developmental stages on plate. Keywords = ammonia Keywords = metabolism Keywords = yeast Keywords = stress Keywords = transcriptome

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Claude Jacq 

PROVIDER: E-GEOD-1454 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Sok2p transcription factor is involved in adaptive program relevant for long term survival of Saccharomyces cerevisiae colonies.

Váchová Libuse L   Devaux Frederic F   Kucerová Helena H   Ricicová Markéta M   Jacq Claude C   Palková Zdena Z  

The Journal of biological chemistry 20040630 36


Volatile ammonia functions as a long range alarm signal important for the transition of yeast colonies to their adaptive alkali developmental phase and for their consequent long term survival. Cells of aged Saccharomyces cerevisiae sok2 colonies deleted in the gene for Sok2p transcription factor are not able to release a sufficient amount of ammonia out of the cells, they are more fragile than cells of wild type colonies, and they exhibit a survival defect. Genome-wide analysis on gene expressio  ...[more]

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