Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Array CGH analysis of glioblastoma spheroid cultures

ABSTRACT: The goal of this study was to investigate genomic aberrations of glioblastoma spheroid cultures. Keywords: Comparative genomic hybridization We performed array comparative genomic hybridization of spheroid cultures derived from 20 glioblastomas using as a reference DNA from healthy donors.

ORGANISM(S): Homo sapiens

SUBMITTER: Aurelie Ernst

PROVIDER: E-GEOD-14822 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Array CGH analysis of single spheroids from glioblastoma spheroid cultures

Project description:The goal of this study was to investigate genomic aberrations of glioblastoma spheroid cultures. Keywords: Comparative genomic hybridization We performed array comparative genomic hybridization of spheroid cultures derived from 2 glioblastoma spheroid cultures using as a reference DNA from healthy donors.

2010-05-14 | E-GEOD-14821 | biostudies-arrayexpress

Molecular analysis of glioblastoma stem cell-like spheroid cultures identifies novel tumor-relevant genes

Project description:This SuperSeries is composed of the following subset Series: GSE14818: Gene expression analysis of glioblastoma spheroid cultures I GSE14819: Array CGH analysis of glioblastoma serum grown adherent cultures GSE14820: Array CGH analysis of glioblastoma cell lines GSE14821: Array CGH analysis of single spheroids from glioblastoma spheroid cultures GSE14822: Array CGH analysis of glioblastoma spheroid cultures GSE14823: Array CGH analysis of glioblastomas GSE16666: Gene expression analysis of glioblastoma spheroid cultures II Refer to individual Series

2010-02-12 | E-GEOD-14824 | biostudies-arrayexpress

Array CGH analysis of glioblastoma serum grown adherent cultures

Project description:We performed array comparative genomic hybridization of spheroid cultures derived from 13 glioblastomas. Keywords: comparative genomic hybridization Comparative genomic hybridization of spheroid cultures derived from glioblastomas using as a reference DNA from healthy donors.

2010-05-14 | E-GEOD-14819 | biostudies-arrayexpress

Array CGH analysis of glioblastomas

Project description:The goal of this study was to investigate genomic aberrations of glioblastoma patients. Keywords: Comparative genomic hybridization We performed array comparative genomic hybridization of 7 glioblastomas using as a reference DNA from healthy donors.

2010-02-12 | E-GEOD-14823 | biostudies-arrayexpress

Array CGH analysis of glioblastoma cell lines

Project description:The goal of this study was to investigate genomic aberrations of glioblastoma cell lines. Keywords: Comparative genomic hybridization We performed array comparative genomic hybridization of 8 glioblastoma cell lines

2010-02-12 | E-GEOD-14820 | biostudies-arrayexpress

Human ependymoma samples, Subgrouping [aCGH - German Cancer Research Center human 33K BAC array]

Project description:Whole-genome array comparative genomic hybridization (aCGH) of human ependymoma tumors. DOP-PCR products were spotted in triplicate onto NexterionTM Slide E epoxysilane-coated slides (PEQLAB, Erlangen, Germany) using a spotting robot (VersArray ChipWriterTM Pro system,BioRad, Munich, Germany) at 20C and 40% humidity. After spotting, slides were cross-linked,baked for 1 hr at 80C, and cross-linked again. Fresh frozen tumor material was collected during tumor resection. Copy number aberrations represent the status at diagnosis.

2011-08-14 | E-GEOD-27286 | biostudies-arrayexpress

Delineation of Two Clinically and Molecularly Distinct Subgroups of Posterior Fossa Ependymoma.

Project description:Despite histological similarity of ependymomas from throughout the neuraxis, the disease likely comprises multiple independent entities, each with a distinct molecular pathogenesis. Transcriptional profiling of two large independent cohorts of ependymomas reveals the existence of two demographically, transcriptionally, genetically and clinically distinct groups of posterior fossa (PF) ependymoma. Group A patients are younger, have laterally located tumors with a balanced genome, and are much more likely to exhibit recurrence, metastasis, and death as compared to Group B patients. Identification and optimization of immunohistochemical markers for PF ependymoma subgroups allowed validation of our findings on a third group of independent ependymomas using a human ependymoma tissue microarray, and provides a tool for prospective prognostication and stratification of PF ependymoma patients. This SuperSeries is composed of the following subset Series: GSE27283: Human ependymoma samples [expression] GSE27286: Human ependymoma samples, Subgrouping [aCGH - German Cancer Research Center human 33K BAC array] Refer to individual Series

2011-08-14 | E-GEOD-27287 | biostudies-arrayexpress

Gene expression analysis of glioblastoma spheroid cultures II

Project description:Microarray-based gene expression analysis identified genes differentially expressed in 10 glioblastoma spheroid cultures compared to a non-neoplastic spheroid culture isolated from the bulbus olfactorius In this study, a set of 10 glioblastoma spheroid cultures was used to acquire expression profiles of a total of 17 093 transcripts, leading to the identification of differentially expressed genes compared to a non-neoplastic brain spheroid culture

2010-02-12 | E-GEOD-16666 | biostudies-arrayexpress

Gene expression analysis of glioblastoma spheroid cultures I

Project description:Microarray-based gene expression analysis identified genes differentially expressed in 10 glioblastoma spheroid cultures compared to normal brain. In this study, a set of 10 glioblastoma spheroid cultures was used to acquire expression profiles of a total of 16 441 transcripts, leading to the identification of differentially expressed genes compared to normal brain by Significance Analysis of Microarray dada.

2010-02-12 | E-GEOD-14818 | biostudies-arrayexpress

MicroRNAs and mRNAs differentially expressed in 5 glioblastoma spheroid cultures upon ATRA treatment

Project description:Microarray-based gene expression analysis identified microRNAs and mRNAs differentially expressed in 5 glioblastoma spheroid cultures upon ATRA treatment. In this study, a set of 5 glioblastoma spheroid cultures was used to acquire microRNA expression profiles, leading to the identification of differentially expressed microRNAs between untreated and ATRA-treated cultures. In this study, a set of 5 glioblastoma spheroid cultures was used to acquire expression profiles of a total of 16,651 transcripts, leading to the identification of differentially expressed genes between untreated and ATRA-treated cultures by Significance Analysis of Microarray data.

2010-07-20 | E-GEOD-17227 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data