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Gene expression analysis of glioblastoma spheroid cultures II

ABSTRACT: Microarray-based gene expression analysis identified genes differentially expressed in 10 glioblastoma spheroid cultures compared to a non-neoplastic spheroid culture isolated from the bulbus olfactorius In this study, a set of 10 glioblastoma spheroid cultures was used to acquire expression profiles of a total of 17 093 transcripts, leading to the identification of differentially expressed genes compared to a non-neoplastic brain spheroid culture

ORGANISM(S): Homo sapiens

SUBMITTER: Aurelie Ernst

PROVIDER: E-GEOD-16666 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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High-resolution nucleosome mapping reveals transcription-dependent promoter packaging.

Weiner Assaf A Hughes Amanda A Yassour Moran M Rando Oliver J OJ Friedman Nir N

Genome research 20091021 1

Genome-wide mapping of nucleosomes has revealed a great deal about the relationships between chromatin structure and control of gene expression, and has led to mechanistic hypotheses regarding the rules by which chromatin structure is established. High-throughput sequencing has recently become the technology of choice for chromatin mapping studies, yet analysis of these experiments is still in its infancy. Here, we introduce a pipeline for analyzing deep sequencing maps of chromatin structure an ...[more]

PMID: 19846608

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