Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of human pancreatic ductal cells from pancreatic ductal carcinoma patients and healthy subjects

ABSTRACT: RNA was purified from pancreatic ductal cells, and was subjected to microarray experiments with HGU133 A&B arrays.

ORGANISM(S): Homo sapiens

DISEASE(S): pancreatic ductal carcinoma

SUBMITTER: Hiroyuki Mano 

PROVIDER: E-GEOD-1542 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Experimental trial for diagnosis of pancreatic ductal carcinoma based on gene expression profiles of pancreatic ductal cells.

Ishikawa Madoka M   Yoshida Koji K   Yamashita Yoshihiro Y   Ota Jun J   Takada Shuji S   Kisanuki Hiroyuki H   Koinuma Koji K   Choi Young Lim YL   Kaneda Ruri R   Iwao Toshiyasu T   Tamada Kiichi K   Sugano Kentaro K   Mano Hiroyuki H  

Cancer science 20050701 7

Pancreatic ductal carcinoma (PDC) remains one of the most intractable human malignancies, mainly because of the lack of sensitive detection methods. Although gene expression profiling by DNA microarray analysis is a promising tool for the development of such detection systems, a simple comparison of pancreatic tissues may yield misleading data that reflect only differences in cellular composition. To directly compare PDC cells with normal pancreatic ductal cells, we purified MUC1-positive epithe  ...[more]

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