Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Garry Fathman
PROVIDER: E-GEOD-15753 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Creusot Rémi J RJ Yaghoubi Shahriar S SS Chang Pearl P Chia Justine J Contag Christopher H CH Gambhir Sanjiv S SS Fathman C Garrison CG
Blood 20090410 26
Because of their potent immunoregulatory capacity, dendritic cells (DCs) have been exploited as therapeutic tools to boost immune responses against tumors or pathogens, or dampen autoimmune or allergic responses. Murine bone marrow-derived DCs (BM-DCs) are the closest known equivalent of the blood monocyte-derived DCs that have been used for human therapy. Current imaging methods have proven unable to properly address the migration of injected DCs to small and deep tissues in mice and humans. Th ...[more]