Ontology highlight
ABSTRACT:
ORGANISM(S): Macaca mulatta
SUBMITTER: Cynthia Bethea
PROVIDER: E-GEOD-16169 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Bethea Cynthia L CL Reddy Arubala P AP
Journal of neurochemistry 20080107 4
We sought the effect of estradiol (E) and progesterone (P) on survival gene expression in laser captured serotonin neurons and in the dorsal raphe region of monkeys with cDNA array analysis. Spayed rhesus macaques were treated with either placebo, E or E + P via Silastic implant for 1 month prior to killing. First, RNA from a small block of midbrain containing the dorsal raphe was hybridized to Rhesus Gene Chips (n = 3/treatment). There was a significant change in 854 probe sets with E +/- P tre ...[more]