Ontology highlight
ABSTRACT:
ORGANISM(S): Rattus norvegicus
SUBMITTER: Benito Yard
PROVIDER: E-GEOD-16483 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Hoeger S S Bergstraesser C C Selhorst J J Fontana J J Birck R R Waldherr R R Beck G G Sticht C C Seelen M A MA van Son W J WJ Leuvenink H H Ploeg R R Schnuelle P P Yard B A BA
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100105 3
Because the vagus nerve is implicated in control of inflammation, we investigated if brain death (BD) causes impairment of the parasympathetic nervous system, thereby contributing to inflammation. BD was induced in rats. Anaesthetised ventilated rats (NBD) served as control. Heart rate variability (HRV) was assessed by ECG. The vagus nerve was electrically stimulated (BD + STIM) during BD. Intestine, kidney, heart and liver were recovered after 6 hours. Affymetrix chip-analysis was performed on ...[more]