Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Andrew Hinton
PROVIDER: E-GEOD-16681 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Hinton Andrew A Afrikanova Ivka I Wilson Mike M King Charles C CC Maurer Brian B Yeo Gene W GW Hayek Alberto A Pasquinelli Amy E AE
Stem cells and development 20100601 6
Human embryonic stem cells (hESCs) have the potential to differentiate into many adult cell types, and they are being explored as a resource for cell replacement therapies for multiple diseases. In order to optimize in vitro differentiation protocols, it will be necessary to elucidate regulatory mechanisms that contribute to lineage specification. MicroRNAs (miRNAs) are emerging as key regulators of hESC differentiation and embryonic development. In this study, we compare miRNA expression profil ...[more]