Unknown,Transcriptomics,Genomics,Proteomics

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Isometric contractions in skeletal muscle of adult mice


ABSTRACT: Study to examine the effect of a demanding 15 minute whole hindlimb isometric contraction protocol in vivo on changes in gene expression, 4 hours post-contraction. Keywords = skeletal muscle Keywords = isometric contractions

ORGANISM(S): Mus musculus

SUBMITTER: Anne McArdle 

PROVIDER: E-GEOD-1679 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Preconditioning of skeletal muscle against contraction-induced damage: the role of adaptations to oxidants in mice.

McArdle F F   Spiers S S   Aldemir H H   Vasilaki A A   Beaver A A   Iwanejko L L   McArdle A A   Jackson M J MJ  

The Journal of physiology 20040826 Pt 1


Adaptations of skeletal muscle following exercise are accompanied by changes in gene expression, which can result in protection against subsequent potentially damaging exercise. One cellular signal activating these adaptations may be an increased production of reactive oxygen and nitrogen species (ROS). The aim of this study was to examine the effect of a short period of non-damaging contractions on the subsequent susceptibility of muscle to contraction-induced damage and to examine the changes  ...[more]

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