Normal and injured liver sinusoidal endothelial cells
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Hidenori Nonaka
PROVIDER: E-GEOD-1689 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Serial analysis of gene expression in sinusoidal endothelial cells from normal and injured mouse liver.
Nonaka Hidenori H Sugano Sumio S Miyajima Atsushi A
Biochemical and biophysical research communications 20041101 1
Here we describe gene expression profiles of mouse liver sinusoidal endothelial cells (LSECs) revealed by serial analysis of gene expression (SAGE). We prepared SAGE libraries of LSECs from normal and injured liver by CCl(4) administration, and we obtained 32,867 tags from normal and 37,493 tags from injured liver, representing 6011 unique transcripts. CCl(4) administration upregulated several genes related to cell growth and differentiation (Cdkn1a, Irf1, Il4ra, etc.), whereas it downregulated ...[more]
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