Transcription profiling of mouse NIH 3T3 cells, cells treated with cytochalasin D, and cells treated with latrunculin B and cytochalasin D - G-actin switch
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ABSTRACT: We analysed the G-actin regulated transcriptome by gene expression analysis using previously characterised actin binding drugs. We found many known MAL/MRTF-dependent target genes of serum response factor (SRF) as well as unknown directly regulated genes. Experiment Overall Design: Three conditions were used for the microarray analysis: control NIH 3T3 cells, cells treated with cytochalasin D, and cells treated with latrunculin B and cytochalasin D. For each condition, three independent biological replicates were analysed.
ORGANISM(S): Mus musculus
SUBMITTER: Guido Posern
PROVIDER: E-GEOD-17105 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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