Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Nils Cordes
PROVIDER: E-GEOD-17347 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Zschenker Oliver O Streichert Thomas T Hehlgans Stephanie S Cordes Nils N
PloS one 20120411 4
Cell morphology determines cell behavior, signal transduction, protein-protein interaction, and responsiveness to external stimuli. In cancer, these functions profoundly contribute to resistance mechanisms to radio- and chemotherapy. With regard to this aspect, this study compared the genome wide gene expression in exponentially growing cell lines from different tumor entities, lung carcinoma and squamous cell carcinoma, under more physiological three-dimensional (3D) versus monolayer cell cultu ...[more]