Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Amy Molesworth
PROVIDER: E-GEOD-17612 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Maycox P R PR Kelly F F Taylor A A Bates S S Reid J J Logendra R R Barnes M R MR Larminie C C Jones N N Lennon M M Davies C C Hagan J J JJ Scorer C A CA Angelinetta C C Akbar M T MT Hirsch S S Mortimer A M AM Barnes T R E TR de Belleroche J J
Molecular psychiatry 20090303 12
Schizophrenia is a severe psychiatric disorder with a world-wide prevalence of 1%. The pathophysiology of the illness is not understood, but is thought to have a strong genetic component with some environmental influences on aetiology. To gain further insight into disease mechanism, we used microarray technology to determine the expression of over 30 000 mRNA transcripts in post-mortem tissue from a brain region associated with the pathophysiology of the disease (Brodmann area 10: anterior prefr ...[more]