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Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of mouse hematopoietic stems cells and myeloid progenitor cells from wild type and Dnmt1 hypomorph mice shows DNA hypomethylation leads to derepression of myeloerythroid genes

ABSTRACT: Analysis of hematopoietic stem cells (HSC, LSK Flt3-) and myeloid progenitors (MP, LK CD34+) sorted from wildtype and Dnmt1 hypomorph mice Experiment Overall Design: We FACS sorted HSCs and MPs from bone marrow of 8-12 week old wildtype or Dnmt1 hypomorph (Dnmt1-/chip) mice.

ORGANISM(S): Mus musculus

SUBMITTER: Frank Rosenbauer

PROVIDER: E-GEOD-17765 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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DNA hypomethylation leads to derepression of myeloerythroid genes in hematopoietic stem cells (HSC)

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