Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Aaron Sarver
PROVIDER: E-GEOD-18392 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Sarver Aaron L AL French Amy J AJ Borralho Pedro M PM Thayanithy Venugopal V Oberg Ann L AL Silverstein Kevin A T KA Morlan Bruce W BW Riska Shaun M SM Boardman Lisa A LA Cunningham Julie M JM Subramanian Subbaya S Wang Liang L Smyrk Tom C TC Rodrigues Cecilia M P CM Thibodeau Stephen N SN Steer Clifford J CJ
BMC cancer 20091118
<h4>Background</h4>Colon cancer arises from the accumulation of multiple genetic and epigenetic alterations to normal colonic tissue. microRNAs (miRNAs) are small, non-coding regulatory RNAs that post-transcriptionally regulate gene expression. Differential miRNA expression in cancer versus normal tissue is a common event and may be pivotal for tumor onset and progression.<h4>Methods</h4>To identify miRNAs that are differentially expressed in tumors and tumor subtypes, we carried out highly sens ...[more]