Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: C Robtertson
PROVIDER: E-GEOD-1840 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Booth Stephanie S Bowman Christopher C Baumgartner Richard R Sorensen Garrett G Robertson Catherine C Coulthart Michael M Phillipson Clark C Somorjai Rajmund L RL
The Journal of general virology 20041101 Pt 11
Genes that are expressed differentially in the central nervous system of mice during infection with mouse-adapted scrapie agents were identified in this study. cDNA microarrays were used to examine gene-expression profiles at early, middle (preclinical) and late (clinical) time points after inoculation. A number of genes that showed significant changes in expression during the clinical stage of disease were identified. Of these, 138 were upregulated and 20 were downregulated. A smaller number of ...[more]