Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Iain Gallagher
PROVIDER: E-GEOD-18832 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Stephens Nathan A NA Gallagher Iain J IJ Rooyackers Olav O Skipworth Richard J RJ Tan Ben H BH Marstrand Troels T Ross James A JA Guttridge Denis C DC Lundell Lars L Fearon Kenneth C KC Timmons James A JA
Genome medicine 20100115 1
<h4>Background</h4>Cancer cachexia is a multi-organ tissue wasting syndrome that contributes to morbidity and mortality in many cancer patients. Skeletal muscle loss represents an established key feature yet there is no molecular understanding of the disease process. In fact, the postulated molecular regulators of cancer cachexia originate largely from pre-clinical models and it is unclear how these translate to the clinical environment.<h4>Methods</h4>Rectus abdominis muscle biopsies were obtai ...[more]