Light activation of the sigmaB-mediated general stress-response of Bacillus subtilis
Ontology highlight
ABSTRACT:
ORGANISM(S): Bacillus subtilis
SUBMITTER: Remco Kort
PROVIDER: E-GEOD-19464 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Red light activates the sigmaB-mediated general stress response of Bacillus subtilis via the energy branch of the upstream signaling cascade.
Avila-Pérez Marcela M van der Steen Jeroen B JB Kort Remco R Hellingwerf Klaas J KJ
Journal of bacteriology 20091130 3
The sigma(B)-dependent general stress response in the common soil bacterium Bacillus subtilis can be elicited by a range of stress factors, such as starvation or an ethanol, salt, or heat shock, via a complex upstream signaling cascade. Additionally, sigma(B) can be activated by blue light via the phototropin homologue YtvA, a component of the environmental branch of the signaling cascade. Here we use a reporter-gene fusion to show that sigma(B) can also be activated by red light via the energy ...[more]
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An important transcription factor of B.subsilis is sigma B
. Liebal et al. (2012) have performed experiments in B.subtilis wild type and mutant straits to test and validate a mathematical model of the dynamics of sigma B
activity. The following three models were constructed and their ability to fit the experimental data were tested. 1) Transcription inhibition model (MODEL1212180000), 2) sigma B
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This model is described in the article:
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Abstract:
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Figure 3a of the reference article has been reproduced. beta-galactosidase (lacz in model) activity at different concentrations of IPTG (100M, 200M and 1000M) has been reproduced. SED-ML (Simulation Experiment Description Markup Language) file is available for this model (see curation tab).
This model is hosted on BioModels Database
and identified
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.
To cite BioModels Database, please use: BioModels Database: An enhanced, curated and annotated resource
for published quantitative kinetic models
.
To the extent possible under law, all copyright and related or
neighbouring rights to this encoded model have been dedicated to the public
domain worldwide. Please refer to CC0 Public Domain
Dedication
for more information.
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activity. The following three models are constructed and their ability to fit the experimental data were tested. 1) Transcription inhibition model (MODEL1212180000), 2) sigma B
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This model is described in the article:
Proteolysis of beta-galactosidase following SigmaB activation in Bacillus subtilis.
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2012 Jun;8(6):1806-14.
Abstract:
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This model is hosted on BioModels Database
and identified
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.
To cite BioModels Database, please use: BioModels Database: An enhanced, curated and annotated resource
for published quantitative kinetic models
.
To the extent possible under law, all copyright and related or
neighbouring rights to this encoded model have been dedicated to the public
domain worldwide. Please refer to CC0 Public Domain
Dedication
for more information.
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activity. The following three models were constructed and their ability to fit the experimental data were tested. 1) Transcription inhibition model (MODEL1212180000), 2) sigma B
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This model is described in the article:
Proteolysis of beta-galactosidase following SigmaB activation in Bacillus subtilis.
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This model is hosted on BioModels Database
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.
To cite BioModels Database, please use: BioModels Database: An enhanced, curated and annotated resource
for published quantitative kinetic models
.
To the extent possible under law, all copyright and related or
neighbouring rights to this encoded model have been dedicated to the public
domain worldwide. Please refer to CC0 Public Domain
Dedication
for more information.
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