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Expression data from wild-type FY4 and GCR2 deletion strain

ABSTRACT: Expression data from wild-type FY4 and GCR2 deletion strain. Impact of the transcription factor Gcr2p on mRNA expression was investigated in the corresponding deletion strain in exponentially growing glucose minimal medium batch cultures. Both streins were grown on glucose minimal medium and harvested during exponential growth for transcript analysis

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Ana Oliveira

PROVIDER: E-GEOD-19569 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Unraveling condition-dependent networks of transcription factors that control metabolic pathway activity in yeast.

Fendt Sarah-Maria SM Oliveira Ana Paula AP Christen Stefan S Picotti Paola P Dechant Reinhard Christoph RC Sauer Uwe U

Molecular systems biology 20101101

Which transcription factors control the distribution of metabolic fluxes under a given condition? We address this question by systematically quantifying metabolic fluxes in 119 transcription factor deletion mutants of Saccharomyces cerevisiae under five growth conditions. While most knockouts did not affect fluxes, we identified 42 condition-dependent interactions that were mediated by a total of 23 transcription factors that control almost exclusively the cellular decision between respiration a ...[more]

PMID: 21119627

Publication: 1/2

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