Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Kimberly Bussey
PROVIDER: E-GEOD-19776 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Demeure Michael J MJ Coan Kathryn E KE Grant Clive S CS Komorowski Richard A RA Stephan Elizabeth E Sinari Shripad S Mount David D Bussey Kimberly J KJ
Surgery 20131201 6
<h4>Background</h4>Adrenocortical carcinoma (ACC) is associated with poor survival rates. The objective of the study was to analyze ACC gene expression profiling data for prognostic biomarkers and therapeutic targets.<h4>Methods</h4>We profiled 44 ACC and 4 normal adrenals on Affymetrix U133 Plus 2 expression microarrays. Pathway and transcriptional enrichment analysis was performed. Protein levels were determined by Western blot. Drug efficacy was assessed against ACC cell lines. Previously pub ...[more]