Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Howard Yang
PROVIDER: E-GEOD-20123 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Yang Howard H HH Hu Nan N Wang Chaoyu C Ding Ti T Dunn Barbara K BK Goldstein Alisa M AM Taylor Philip R PR Lee Maxwell P MP
PloS one 20100223 2
Recent studies have shown a genetic influence on gene expression variation, chromatin, and DNA methylation. However, the effects of genetic background and tissue types on DNA methylation at the genome-wide level have not been characterized extensively. To study the effect of genetic background and tissue types on global DNA methylation, we performed DNA methylation analysis using the Affymetrix 500K SNP array on tumor, adjacent normal tissue, and blood DNA from 30 patients with esophageal squamo ...[more]