Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Transcription profiling of human bronchoalveolar lavage samples collected from lung transplant recipients with rejection states determined at the time of sample collection

ABSTRACT: Bronchoalveolar lavage samples collected from lung transplant recipients. Numeric portion of sample name is an arbitrary patient ID and AxBx number indicates the perivascular (A) and bronchiolar (B) scores from biopsies collected on the same day as the BAL fluid was collected. Several patients have more than one sample in this series and can be determined by patient number followed by a lower case letter. Acute rejection state is determined by the combined A and B score - specifically, a combined AB score of 2 or greater is considered an acute rejection.

ORGANISM(S): Homo sapiens

SUBMITTER: Jeff Lande

PROVIDER: E-GEOD-2018 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Gene expression profiling of bronchoalveolar lavage cells in acute lung rejection.

Gimino Vincent J VJ Lande Jeffrey D JD Berryman Todd R TR King Richard A RA Hertz Marshall I MI

American journal of respiratory and critical care medicine 20030904 10

Lung transplantation is effective for many diseases that are unresponsive to other therapy. However, long-term survival of recipients is limited by the development of bronchiolitis obliterans syndrome. Acute rejection is a major risk factor for bronchiolitis obliterans syndrome, but noninvasive biomarkers have not been identified. To address this deficiency, gene expression microarrays were performed using bronchoalveolar lavage cells of lung transplant recipients with acute rejection (n = 7) an ...[more]

PMID: 12958056

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Dataset Information

Transcription profiling of human bronchoalveolar lavage samples collected from lung transplant recipients with rejection states determined at the time of sample collection

Publications

Gene expression profiling of bronchoalveolar lavage cells in acute lung rejection.

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