Dataset Information
Assessment of mutation on expression levels
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Peter Haverty
PROVIDER: E-GEOD-20578 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
The mutation spectrum revealed by paired genome sequences from a lung cancer patient.
Nature 20100501 7297
Lung cancer is the leading cause of cancer-related mortality worldwide, with non-small-cell lung carcinomas in smokers being the predominant form of the disease. Although previous studies have identified important common somatic mutations in lung cancers, they have primarily focused on a limited set of genes and have thus provided a constrained view of the mutational spectrum. Recent cancer sequencing efforts have used next-generation sequencing technologies to provide a genome-wide view of muta ...[more]
