Dataset Information
Transcription profiling of mouse 3T3-F442A adipocytes treated with or without growth hormone (GH) to identify a mechanism for regulation of activating transcription factor 3 by GH
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Jessica Schwartz
PROVIDER: E-GEOD-2120 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Profiles of growth hormone (GH)-regulated genes reveal time-dependent responses and identify a mechanism for regulation of activating transcription factor 3 by GH.
The Journal of biological chemistry 20051201 7
In examination of mechanisms regulating metabolic responses to growth hormone (GH), microarray analysis identified 561 probe sets showing time-dependent patterns of expression in GH-treated 3T3-F442A adipocytes. Biological functions significantly over-represented among GH-regulated genes include regulators of transcription at early times, and lipid biosynthesis, cholesterol biosynthesis, and mediators of immune responses at later times (48 h). One novel GH-induced gene encodes activating transcr ...[more]
